Five Cannabinoids (Besides THC and CBD)

Five Cannabinoids (Besides THC and CBD) You Might Not Know About

Most medical cannabis patients are familiar with THC and CBD the two most common chemical compounds you can find in a cannabis plant. THC, or delta-9-tetrahydrocannabinol, is marijuana's main psychoactive element that gives you the feeling of euphoria. CBD, or cannabidiol, is the non-psychoactive chemical that is believed to be responsible for the majority of cannabis' miraculous medicinal effects: from reducing pain to easing nausea to stopping severe seizures. But there are a lot more to cannabis: we will tell you about five cannabinoids that are less famous but still extremely beneficial to our health.

CBC is a non-psychoactive cannabis compound, which means it won't get you high. This cannabinoid may be helpful in reducing the severances of pain and inflammation. CBC may also help slow down the growth of cancer cells.

It looks like CBC really loves sunlight and hot weather because it is easier to find this cannabinoid in cannabis strains that were grown in warmer climes. The average content of CBC in marijuana strains grown in colder regions is less than 1 percent.

CBG is also a non-psychoactive chemical compound, plus, it is one of the cannabinoids that can be easily found in hemp. Most cannabis strains, however, contain less that 1 percent of cannabigerol.

The main medicinal benefit of CBG is its ability to inhibit the growth of cancerous and tumorous cells. CBG is also believed to be helpful in reducing pain and inflammation.

It is pretty difficult to find even the smallest amounts of CBN in live cannabis plants. This chemical compound shows itself when the levels of THC begin to decrease; mostly in harvested cannabis when it is exposed to air and light.

CBN is considered to be mildly psychoactive and is usually used in combination with CBD. Together, these two compounds work best for combating insomnia, reducing muscle spasms and pain.

The chemical structure of THCV, also known as THV, is quite similar to the one of THC. Just like THC, THCV is psychoactive but has a bit different effects: while it still makes you feel high, your head and thoughts remain clear.

As for the medicinal benefits of THCV, the chemical is believed to be able to:

    Reduce the severances of seizures;
    Suppress appetite;
    Normalize blood sugar levels.

CBDV is a homolog of CBD that is most frequently found in wild cannabis strains from Nepal and India. Domesticated marijuana plants contain only trace amounts of the chemical.

Just like CBD, CBDV does not have any psychoactive effects and therefore cannot get you high. What it can do is reduce the quantity and severances of seizures in patients with epilepsy.

These five cannabinoids are not the only chemicals contained in cannabis plants. There are plenty of others, and their medicinal potential is yet to be explored.

Cannabis For Brain tumor First Human Trials Begins

Cannabis For Brain tumor First Human Trials Begins

Cannabis For Brain tumor Sativex is an oral spray made from ingredients derived from the whole cannabis plant. The two main compounds in cannabis CBD and THC Brain tumor are present in Sativex in an equal 1:1 ratio.

Both cannabis compounds (known as cannabinoids) have shown anti-cancer properties in pre-clinical studies, and seem to be effective against a wide range of cancers.Brain tumor Anecdotal reports also suggest that cannabis and cannabinoids have the ability to fight cancer.However, GW Pharmaceuticals is the first company to initiate clinical research on cannabis-based medicine as a cancer therapy.

“We are very excited about moving this compound into more humans study and the prospects of cannabinoids as new anti-cancer treatments. This is GW’s first clinical study of cannabinoids as a potential treatment to inhibit tumor growth.”The company plans to investigate Brain tumor Sativex as an add-on to the standard chemotherapy agent temozolomide, rather than a stand-alone. According to GW Pharmaceuticals, pre-clinical research suggests that cannabinoids can improve the anti-cancer ability of temozolomide.

The Phase 1b/2a trial announced on Monday will involve 20 patients with recurrent glioblastoma multiforme (GBM), an aggressive and rare form of brain cancer that accounts for about 50% of all brain cancers diagnosed in the U.S. each year. The trial will first have to prove the safety of the combined treatment regimen before further research can be done on its effectiveness.

In the U.S., clinical trials of cannabinoids for cancer are also expected in the near future. Sean McAllister, Ph.D and his colleagues at California Pacific Medical Center hope to begin the first human studies of CBD for breast cancer within the next 12 months.Sativex is currently approved in more than 20 countries for the treatment of multiple sclerosis symptoms and is also being studied as a treatment for cancer pain.

While Sativex has been GW’s leading product, the company has a number of other cannabinoid-based drugs in its pipeline, including an epilepsy drug called Epidiolex.Epidiolex, which contains more than 98 percent CBD, recently began clinical trials in the U.S. and U.K as a treatment for pediatric epilepsy.